Key result
Holzapfel and four-fiber-family models best fit porcine pericardium tensile data in fluid-structure interaction simulations.
Why the study?
Improving bioprosthetic aortic valve durability and hemodynamic performance requires understanding porcine pericardium biomechanics and deriving constitutive models for fluid-structure interaction simulations.
Absolute Event Rate: 1.77% vs 1.94%
The choice of constitutive model for porcine pericardium affects FSI simulation predictions of bioprosthetic aortic valve hemodynamics, with the Fung, four-fiber-family, and HGO models showing the best fit to experimental data.
Authors
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May enhance FSI simulation accuracy for porcine pericardial valves; leaves open human validation.
Matjeka et al. (2026) studied Aortic valve disease (bioprosthetic valve design) (n=9). Anisotropic hyperelastic constitutive models (Holzapfel 2005 and four-fiber-family) vs. Other constitutive models was evaluated on Peak velocity in fluid-structure interaction simulations. The Holzapfel (2005) and four-fiber-family models best fitted the equibiaxial tensile data of porcine pericardium, yielding peak velocities of 1.77 m/s and 1.94 m/s respectively in fluid-structure interaction simulations.
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