Key result
Evaluating biomechanical and morphological changes in porcine heart valve conduits according to donor weight and age is valuable for developing age-targeted tissue engineering therapies.
Population
Acellular porcine aortic and pulmonary valve conduits from transgenic pigs of differing weight and age
Design
Preclinical
Authors
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May inform age-specific porcine valve scaffold selection; leaves open human translation.
Studying age- and weight-related biomechanical changes in porcine heart valve conduits may inform age-targeted tissue engineering therapies for valve prostheses.
Wilczek et al. (2014) studied Heart valve tissue engineering. Acellular porcine aortic and pulmonary valve conduits was evaluated on Biomechanical and hemodynamical properties. Evaluating biomechanical and morphological changes in porcine heart valve conduits according to donor weight and age is valuable for developing age-targeted tissue engineering therapies.