Why the study?
Does smoking alter autonomic nervous system balance, cardiac remodeling, and 24-hour blood pressure profiles in patients with stage II essential hypertension?
Population
100 patients (53 men, 47 women) with essential hypertension stage II and low additional cardiovascular risk.
Comparison
Smoking vs Non-smokers (n=70)
Design
Cross-sectional
Authors
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Smoking associated with adverse autonomic and structural changes in stage II hypertension; hypothesis-generating and should not yet change practice.
Does smoking alter autonomic nervous system balance, cardiac remodeling, and 24-hour blood pressure profiles in patients with stage II essential hypertension?
In patients with stage II hypertension, smoking is associated with increased sympathetic nervous system activity, adverse cardiac remodeling, and higher 24-hour ambulatory blood pressure despite similar office blood pressure readings.
Poznanskaya et al. (2013) studied this question.
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