The report adds 3 cases of Kimura's disease in the orofacial region to the literature and discusses its relationship with angiolymphoid hyperplasia with eosinophilia.
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Adds sparse orofacial Kimura's disease cases; leaves open its distinction from angiolymphoid hyperplasia with eosinophilia.
Kimura's disease, eosinophilic granuloma of soft tissues, is a chronic inflammatory condition and appears as subcutaneous tumor-like nodules in the head and neck regions. Histopathologically, it is characterized by the presence of lymphoid follicles, marked infiltration of eosinophils, fibrosis and vascular proliferation. This disease occurring in the orofacial region is relatively rare, only 14 cases having been previously reported. We describe 3 additional cases of Kimura's disease and discuss these in relation to angiolymphoid hyperplasia with eosinophilia.
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Iguchi et al. (1986) studied this question.
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