July 23, 2012Clinical and Applied Thrombosis/Hemostasis

The Effects of Vitamin D Deficiency on Atrial Fibrillation

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Why the study?

Is there an association between vitamin D deficiency and different types of atrial fibrillation?

Population

298 individuals, comprising 102 patients with nonvalvular chronic AF without other cardiovascular disease…

Comparison

Nonvalvular and valvular atrial fibrillation vs Healthy controls in sinus rhythm

Design

Case-control

Authors

MDMehmet DemirŞanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi UUUmut UyanGeneral / Preventive / Lipids MMMehmet MelekVan Yüzüncü Yıl Üniversitesi

Discussion

Member takes

Implication

Nonvalvular AF was associated with lower vitamin D; hypothesis-generating and should not change practice or prompt supplementation.

Structured PICO

Is there an association between vitamin D deficiency and different types of atrial fibrillation?

Population

298 individuals, comprising 102 patients with nonvalvular chronic AF without other cardiovascular disease (mean age 62.51 ± 5.88), 96 patients with AF associated with mitral valve disease (mean age 61.51 ± 5), and 100 age-matched healthy controls in sinus rhythm (mean age 61.35 ± 5.44).

Intervention

Nonvalvular and valvular atrial fibrillation (disease exposure)

Comparator

Healthy controls in sinus rhythm

Outcome

25-hydroxyvitamin D (25-OHD) levelssurrogate

Nonvalvular atrial fibrillation is associated with significantly lower levels of vitamin D compared to valvular AF and healthy controls.

Cite This Study

Demir et al. (2012) studied this question.

synapsesocial.com/papers/6a83335d8b169f476ee8e49b https://doi.org/10.1177/1076029612453762

Topics

Atrial fibrillation Persistent AF management Echocardiography Anticoagulation in AF

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