Understanding the pharmacological differences among beta-blockers allows for more tailored and effective treatment choices.
May guide individualized beta-blocker selection by profile; leaves open head-to-head outcome trials.
The six currently available beta-adrenergic blocking agents have significant and clinically important differences in their potency, selectivity, partial agonist effect, lipid solubility, and cost. These differences account for many of the observed variations in drug action and dosage scheduling as well as for some of the side effects. Careful choices within this group may lead to more effective treatment.
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Vlietstra et al. (1984) studied this question.
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