What question did this study set out to answer?

To review procedural methods, device specifications, and early clinical success rates of transcatheter aortic valve implantation for elderly patients with severe aortic stenosis facing prohibitive surgical risk.

January 1, 2010Circulation JournalOpen Access

Transcatheter Aortic Valve Implantation in High-Risk Patients With Severe Aortic Stenosis

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Population

Elderly patients with severe aortic stenosis considered high risk for surgery due to high complication rates.

Design

Review

Authors

HHHidehiko HaraToho University RSRobert S. SchwartzGeneral Cardiology

Discussion

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Implication

High acute success supports TAVI feasibility in expert hands; Level 5 data leave durability, comparisons, and broader use open.

Key Points

To review procedural methods, device specifications, and early clinical success rates of transcatheter aortic valve implantation for elderly patients with severe aortic stenosis facing prohibitive surgical risk.
Reviewed global clinical adoption and outcomes across more than 15,000 patients treated worldwide through April 2010.
Evaluated procedural success and deployment mechanics across transfemoral and transapical approaches using balloon-expandable and self-expanding valve systems.
Edwards SAPIEN valve implantation achieved an acute procedural success rate of 95.4% via the transfemoral approach and 92.7% via the transapical approach.
CoreValve ReValving system implantation demonstrated an acute procedural success rate of 98.2% when performed by experienced operators.

Structured PICO

Population

Elderly patients with severe aortic stenosis considered high risk for surgery due to high complication rates.

Intervention

Transcatheter aortic valve implantation (TAVI) using balloon-expandable (e.g., Edwards SAPIEN) or self-expanding (e.g., CoreValve ReValving system) percutaneous aortic valves.

TAVI has emerged as a highly successful, less-invasive alternative to surgical aortic valve replacement for elderly patients with severe aortic stenosis who are at high surgical risk.

Cite This Study

Hara et al. (2010) studied this question.

synapsesocial.com/papers/6a83374188eff2bd7beff060 https://doi.org/10.1253/circj.cj-10-0557

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Transcatheter Aortic Valve Implantation in High-Risk Patients With Severe Aortic Stenosis

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Transcatheter Aortic Valve Implantation in High-Risk Patients With Severe Aortic Stenosis

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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