Why the study?
Does isoflurane reduce myocardial infarct size in a dose-dependent manner in a canine model of ischemia-reperfusion?
Does isoflurane reduce myocardial infarct size in a dose-dependent manner in a canine model of ischemia-reperfusion?
Isoflurane provides cardioprotection against myocardial infarction in a canine model, with concentrations as low as 0.25 MAC being effective and higher concentrations showing greater efficacy during low coronary collateral blood flow.
No takes yet. Share an insight, caveat, or question.
Isoflurane may reduce infarct size in canine ischemia-reperfusion; leaves open translation to human perioperative cardioprotection.
Kehl et al. (2002) studied this question.