Population
Goldfish heart ventricles
Comparison
Exposure to sodium-free, calcium-free, or… vs Standard sodium-containing saline or baseline…
Design
Preclinical
Authors
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Hypothesis-generating for Na-Ca exchange in fish cardiac Ca2+ handling; leaves open relevance to mammalian myocardium.
The study suggests that ATP-dependent Na-Ca exchange plays a role in internal Ca2+ homeostasis in goldfish ventricles, potentially co-operating with a Na-independent active mechanism.
Busselen et al. (1978) studied this question.
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