Why the study?
Does mitral transcatheter edge-to-edge repair (M-TEER) under prolonged Impella support improve clinical outcomes and allow for optimization of guideline-directed medical therapy in patients with severe mitral regurgitation and severe LV dysfunction?
Does mitral transcatheter edge-to-edge repair (M-TEER) under prolonged Impella support improve clinical outcomes and allow for optimization of guideline-directed medical therapy in patients with severe mitral regurgitation and severe LV dysfunction?
Performing M-TEER under prolonged mechanical circulatory support may provide a protected period for ventricular adaptation and optimization of guideline-directed medical therapy in patients with severe mitral regurgitation and extreme left ventricular dysfunction.
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Shiba et al. (2026) conducted an editorial in Severe mitral regurgitation with severely reduced left ventricular dysfunction. Mitral transcatheter edge-to-edge repair (M-TEER) with Impella 5.0 support was evaluated.
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