Why the study?
Marfan syndrome is associated with adverse pregnancy events, notably aortic dissection, and clinical experience with pregnancy following Personalised External Aortic Root Support is limited.
This case report demonstrates the feasibility of successful pregnancy following Personalised External Aortic Root Support (PEARS) in a patient with Marfan syndrome.
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Supports feasibility of pregnancy after PEARS in Marfan syndrome; leaves open broader safety assessment pending larger cohorts.
Marfan syndrome (MFS) is linked with adverse pregnancy events, one of the most significant being aortic dissection. We present a case of a woman with MFS with prior aortic root dilatation who opted for a Personalised External Aortic Root Support (PEARS). To date, she is only the fifth woman to have had this valve-sparing procedure prior to pregnancy. We outline her care in a tertiary centre with multidisciplinary expertise, from preconception through to the postpartum period.
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Coroyannakis et al. (2022) studied this question.
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