Evaluation of Ventricular Arrhythmia Markers in Obstructive Sleep Apnea Syndrome Patients

Ercan Kurt; Hakan Kaya

doi:10.37990/medr.1345326

October 10, 2023Medical RecordsOpen Access

Evaluation of Ventricular Arrhythmia Markers in Obstructive Sleep Apnea Syndrome Patients

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Why the study?

Significant emphasis has been placed on the link between OSAS and ventricular arrhythmias, and the index of cardiac electrophysiological balance (ICEB) represents a new marker to predict ventricular arrhythmia risk.

Does obstructive sleep apnea syndrome increase the index of cardiac electrophysiological balance (ICEB) compared to healthy controls?

Structured PICO

Does obstructive sleep apnea syndrome increase the index of cardiac electrophysiological balance (ICEB) compared to healthy controls?

P

Population

80 participants (40 patients with obstructive sleep apnea syndrome [OSAS] and 40 healthy controls). Exclusions: left or right bundle branch block, extrasinus rhythm, atrioventricular conduction disorder, rheumatoid heart disease, valvular heart disease, thyroid dysfunction, chronic lung disease, chronic kidney disease, anemia, electrolyte disorder, chronic liver disease, chronic infection, systemic autoimmune disease, diabetes, hypertension, coronary heart disease, and use of antidepressants, antipsychotics, or antihistamines.

I

Intervention

Obstructive sleep apnea syndrome (OSAS) exposure

C

Comparator

Healthy controls with no obstructive pathology

O

Outcome

Index of cardiac electrophysiological balance (ICEB), calculated by dividing the QT interval by the QRS duration (QT/QRS)surrogate

Obstructive sleep apnea syndrome is associated with an increased index of cardiac electrophysiological balance (ICEB), suggesting a heightened risk for ventricular arrhythmias that correlates with sleep apnea severity.

Limitations

Lack of electrolyte data, like calcium and magnesium, which can influence QT interval and ventricular repolarization
Normal ranges of ICEB are unknown
Duration of illness in OSAS patients was not recorded

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Implication

OSAS-associated ICEB elevation suggests arrhythmia risk; hypothesis-generating and requires prospective validation before clinical use.

Abstract

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Cite This Study

Kurt et al. (2023) studied this question.

synapsesocial.com/papers/6a8354e6f5518e7e25a0f32a https://doi.org/10.37990/medr.1345326

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Evaluation of Ventricular Arrhythmia Markers in Obstructive Sleep Apnea Syndrome Patients

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Evaluation of Ventricular Arrhythmia Markers in Obstructive Sleep Apnea Syndrome Patients

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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