Population
Rabbit skeletal muscle actin, myosin, and myosin-S1
Design
Preclinical
Authors
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No immediate clinical implications; leaves open applicability to human cardiac myosin and force-generation therapies.
The transition from a disordered transient intermediate to an ordered rigor complex during myosin binding to actin provides structural evidence for the force-generating step in muscle contraction.
Walker et al. (1999) studied this question.
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