Movement of scallop myosin on Nitella actin filaments: regulation by calcium.
Population
Scallop myosin covalently linked to 1-micron beads and a parallel array of actin filaments located on the…
Comparison
Presence of Ca2+ (pCa2+ > 5.84) vs Absence of Ca2+
Design
Preclinical
Authors
Discussion
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Member takes
Implication
Does not support clinical practice changes; leaves open extension of calcium-regulated myosin motility to mammalian cardiac models.
Structured PICO
P
Population
Scallop myosin covalently linked to 1-micron beads and a parallel array of actin filaments located on the cytoplasmic face of a Nitella internodal cell
I
Intervention
Presence of Ca2+ (pCa2+ > 5.84)
C
Comparator
Absence of Ca2+
O
Outcome
Motility of scallop myosin along actin filaments (directed motion and average velocities)surrogate
Scallop myosin motility along actin filaments is regulated by calcium and requires the presence of regulatory light chains.
Cite This Study
Vale et al. (1984) studied this question.