November 1, 2001European Journal of NeuroscienceOpen Access

Characterization of the single‐channel properties of NMDA receptors in laminae I and II of the dorsal horn of neonatal rat spinal cord

View Full Paper

Ask AI

Bookmark

Population

Neonatal rat spinal cord (laminae I and II of the dorsal horn)

Design

Preclinical

Authors

GGG. Mark GreenUniversity College London AGAlasdair J. GibbUniversity College London

Discussion

Member takes

Implication

Unique NMDA properties in neonatal rat cord warrant clinical caution; leaves open subtype-specific roles in human development.

Structured PICO

Population

Neonatal rat spinal cord (laminae I and II of the dorsal horn)

Intervention

NMDA (100 nm) and glycine (10 microm), and ifenprodil

Outcome

Single-channel properties of native NMDA receptorssurrogate

Neonatal laminae I and II NMDA receptors possess unique single-channel properties and high Mg2+ sensitivity, suggesting a complex subunit composition.

Cite This Study

Green et al. (2001) studied this question.

synapsesocial.com/papers/6a8358affb83ad8f1c607010 https://doi.org/10.1046/j.0953-816x.2001.01790.x

View Full Paper

Ask AI

Bookmark

Characterization of the single‐channel properties of NMDA receptors in laminae I and II of the dorsal horn of neonatal rat spinal cord

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Characterization of the single‐channel properties of NMDA receptors in laminae I and II of the dorsal horn of neonatal rat spinal cord

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider