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January 1, 2010North American Journal of Medical SciencesOpen Access

Whole blood viscosity issues VI: Association with blood salicylate level and gastrointestinal bleeding

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Why the study?

Is higher blood salicylate level associated with lower whole blood viscosity?

Population

538 cases from a 10-year database concomitantly tested for haematocrit, total proteins, and blood level of…

Design

Cross-sectional

Authors

ENEzekiel Uba NwoseNCNathan Cann

Discussion

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Overview

Higher salicylate levels were associated with lower viscosity; hypothesis-generating for viscosity as an antiplatelet monitoring parameter.

Structured PICO

Is higher blood salicylate level associated with lower whole blood viscosity?

P
Population
538 cases from a 10-year database concomitantly tested for haematocrit, total proteins, and blood level of salicylate, plus a separate 9 cases of positive faecal occult blood tests.
O
Outcome
Association between blood level of acetylsalicylic acid (salicylate) and whole blood viscosity (WBV)surrogate

Whole blood viscosity inversely correlates with blood salicylate levels and may serve as a useful extrapolated laboratory parameter for monitoring antiplatelet therapy and assessing bleeding risk.

Limitations

  • The review of faecal occult blood is limited by small sample size and selection bias.

Cite This Study

Nwose et al. (2010) studied this question.

synapsesocial.com/papers/6a8358d75ecaa9638130ea46https://doi.org/10.4297/najms.2010.2457
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Also Consider

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