Polyribosomes disaggregate during metaphase in HeLa cells, regardless of whether metaphase is normal or induced by colchicine.
No direct clinical implications; leaves open cell-cycle control of translation in cardiomyocyte regeneration.
Polyribosomes as examined by both sucrose-gradient analysis and electron microscopy disaggregate during metaphase in both normal HeLa cells and those arrested in metaphase by treatment with colchicine.
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Scharff et al. (1966) studied this question.
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