Why the study?
The risk of incident CVD in head and neck squamous cell carcinoma (HNSCC) patients is under-reported.
Are traditional cardiovascular risk factors and cancer-related factors associated with increased 1- and 5-year cardiovascular disease risk in patients with head and neck squamous cell carcinoma?
Population
1,829 HNSCC patients without prevalent CVD at cancer diagnosis
Comparison
HNSCC-related factors and traditional CVD risk factors
Design
Clinical cohort study
Follow-up
Up to 5 years
Authors
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May warrant closer CVD monitoring post-radiation in HNSCC; leaves open causality and practice change pending prospective confirmation.
Are traditional cardiovascular risk factors and cancer-related factors associated with increased 1- and 5-year cardiovascular disease risk in patients with head and neck squamous cell carcinoma?
In patients with head and neck squamous cell carcinoma, traditional risk factors and specific cancer treatments (like radiation) significantly increase the 1- and 5-year risk of cardiovascular disease, highlighting the protective potential of baseline antihypertensive therapy.
Mukherjee et al. (2023) studied this question.
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