Population
A549 human lung tumor cell line
Comparison
Specific siRNAs to decrease NMHC II-C1 vs Decreasing NMHC II-A with siRNA / control
Design
Preclinical
Follow-up
120 h
Authors
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Should not yet change lung cancer practice; hypothesis-generating for NMHC II-C1 as a cytokinesis target in tumor cells.
NMHC II-C1 plays a specific and essential role in cytokinesis and cell proliferation in the A549 human lung tumor cell line.
Jana et al. (2006) studied this question.
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