While so much that is new and important is being accomplished by younger men, it is a great compliment to be asked a second time to deliver one of these lectures; and in venturing to address you again on the same topic as before, I can only plead that in spite of unavoidable and often protracted interruptions, it has continued to engage much of my time and thought. Were every lecturer made to understand that after the lapse of twenty years he would be requested by the Society to give an accounting of his original thesis to see what, if anything, it had amounted to in the interim, such a program would, to say the least, foster conservatism of statement at his inaugural appearance. At a meeting of the Society on December 10, 1910, under the title Dyspituitarism, the attempt was made to throw some light on an obscure subject—the
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Harvey Cushing (1933) studied this question.