Why the study?
Do isoflurane, sevoflurane, and desflurane improve left ventricular relaxation indices in patients with diastolic dysfunction undergoing CABG?
Population
45 patients scheduled for coronary artery bypass grafting surgery with impaired left ventricular relaxation…
Comparison
1 MAC of isoflurane, sevoflurane, or desflurane… vs Comparison between the three inhalational agents.
Design
RCT, randomly received
Follow-up
immediate post-administration
Authors
Loading...
Volatile anesthetics may be chosen interchangeably in CABG with diastolic dysfunction; confirms comparable relaxation benefits and extends agent flexibility in cardiac anesthesia.
Do isoflurane, sevoflurane, and desflurane improve left ventricular relaxation indices in patients with diastolic dysfunction undergoing CABG?
Isoflurane, sevoflurane, and desflurane improve left ventricular relaxation in patients with early diastolic dysfunction, likely due to afterload reduction.
Rupert et al. (2010) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: