Why the study?
Does isoflurane compared to halothane improve hemodynamic profiles when used to control intraoperative hypertension in patients undergoing coronary artery bypass surgery?
Population
20 patients undergoing coronary artery bypass grafting who developed intraoperative hypertension…
Comparison
Isoflurane administered via non-rebreathing… vs Halothane administered via non-rebreathing…
Design
Cohort
Follow-up
Intraoperative (5-10 minutes after treatment)
Authors
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These hemodynamic differences may support isoflurane preference in CABG but should not change practice; leaves open need for RCTs on outcomes.
Does isoflurane compared to halothane improve hemodynamic profiles when used to control intraoperative hypertension in patients undergoing coronary artery bypass surgery?
Isoflurane provides a more favorable hemodynamic profile than halothane for managing intraoperative hypertension during CABG by reducing afterload and increasing cardiac index.
Hess et al. (1983) studied this question.
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