Why the study?
Does isoflurane compared to halothane alter myocardial blood flow and metabolism in patients with coronary artery disease?
Population
20 patients with coronary artery disease before surgical stimulation
Comparison
Isoflurane (1.2%) anesthesia vs Halothane (0.8%) anesthesia
Design
Other
Follow-up
During anesthesia before surgical stimulation
Authors
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May warrant caution with isoflurane in CAD patients; leaves open whether it increases risk versus halothane.
Does isoflurane compared to halothane alter myocardial blood flow and metabolism in patients with coronary artery disease?
Halothane may be preferable to isoflurane in patients with coronary artery disease because isoflurane can induce maldistribution of the coronary circulation and myocardial ischemia.
Khambatta et al. (1988) studied this question.
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