Why the study?
Do halothane and enflurane produce different degrees of myocardial depression in patients with coronary artery disease?
Population
16 adults with ischemic heart disease undergoing coronary artery bypass grafting, excluding those with…
Comparison
Halothane or enflurane anesthesia at 1/2 and 3/4… vs Awake control measurements while breathing 100%…
Design
Cohort
Follow-up
Approximately 1 hour after induction of anesthesia
Authors
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Enflurane may preserve cardiac index better than halothane in CAD; leaves open whether findings apply to modern agents.
Do halothane and enflurane produce different degrees of myocardial depression in patients with coronary artery disease?
Halothane and enflurane have differing hemodynamic effects in patients with ischemic heart disease, with enflurane primarily reducing afterload without depressing cardiac index, unlike halothane.
Delaney et al. (1980) studied this question.
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