Influence of autonomic neuropathy upon left ventricular dysfunction in insulin‐dependent diabetic patients
Why the study?
Does the presence of autonomic neuropathy correlate with left ventricular diastolic dysfunction and altered 24-h blood pressure profiles in type-1 diabetic patients?
Population
19 type-1 diabetic patients
Comparison
Presence of autonomic neuropathy (AN+) vs Absence of autonomic neuropathy (AN-)
Design
Cross-sectional
Authors
Discussion
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Implication
Autonomic neuropathy was associated with diastolic dysfunction and blunted nocturnal BP in type 1 diabetes; leaves open whether screening or intervention improves outcomes.
Structured PICO
Does the presence of autonomic neuropathy correlate with left ventricular diastolic dysfunction and altered 24-h blood pressure profiles in type-1 diabetic patients?
P
Population
19 type-1 diabetic patients
I
Intervention
Presence of autonomic neuropathy (AN+)
C
Comparator
Absence of autonomic neuropathy (AN-)
O
Outcome
Left ventricular function (E/A ratio at echocardiography) and 24-h blood pressure profile (systolic and diastolic BP reductions during sleep)surrogate
Autonomic neuropathy in type-1 diabetic patients is associated with early left ventricular diastolic dysfunction and blunted nocturnal blood pressure reduction.
Cite This Study
Monteagudo et al. (2000) studied this question.