Why the study?
Is diabetic autonomic neuropathy associated with increased left ventricular mass and altered circadian blood pressure in normotensive diabetic patients?
Population
27 normotensive diabetic patients (10 with and 17 without autonomic neuropathy)
Comparison
Presence of diabetic autonomic neuropathy (n=10) vs Absence of diabetic autonomic neuropathy (n=17)
Design
Cross-sectional
Authors
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May flag higher-risk normotensive diabetics; leaves open causal role and need for prospective validation.
Is diabetic autonomic neuropathy associated with increased left ventricular mass and altered circadian blood pressure in normotensive diabetic patients?
Diabetic autonomic neuropathy is associated with increased left ventricular mass and blunted nocturnal blood pressure dipping in normotensive diabetic patients, potentially linking neuropathy to higher cardiovascular mortality.
Gambardella et al. (1993) studied this question.
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