Why the study?
Does antianginal therapy with nitrates and calcium antagonists affect the results of dobutamine-atropine stress echocardiography in patients with coronary artery disease?
Population
26 patients with angiographically assessed coronary artery disease
Comparison
Antianginal therapy during dobutamine-atropine… vs Off antianginal therapy
Design
RCT, random order
Authors
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Clinicians should interpret dobutamine stress echocardiography cautiously on nitrates or calcium antagonists; confirms reduced ischemia detection in CAD.
Does antianginal therapy with nitrates and calcium antagonists affect the results of dobutamine-atropine stress echocardiography in patients with coronary artery disease?
Non-beta-blocker antianginal therapy modestly reduces the sensitivity and severity of ischemia detected by dobutamine-atropine stress echocardiography, though these changes correlate poorly with variations in exercise tolerance.
Dodi et al. (1997) studied this question.
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