Why the study?
Does admission in a later time period (1986-88) with updated therapies improve 28-day and 3-year survival in patients with a first transmural myocardial infarction compared to an earlier period (1978-85)?
Population
1216 consecutive patients with a first transmural myocardial infarction from the REGICOR registry in Girona…
Comparison
Admission during the 1986-1988 period. vs Admission during the 1978-1985 period.
Design
Cohort
Follow-up
3 years
Authors
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Admission in 1986-88 was associated with lower 28-day mortality after first transmural MI; extends temporal trends but leaves 3-year survival unchanged among survivors.
Does admission in a later time period (1986-88) with updated therapies improve 28-day and 3-year survival in patients with a first transmural myocardial infarction compared to an earlier period (1978-85)?
Survival at 28 days after a first transmural myocardial infarction improved in 1986-1988 compared to 1978-1985, likely due to therapeutic refinements and lower initial severity, though 3-year survival among 28-day survivors remained unchanged.
Sala et al. (1995) studied this question.
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