Population
Isolated guinea-pig or rabbit hepatocytes
Design
Preclinical
Authors
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Hypothesis-generating for second-messenger control of hepatocyte ion channels; leaves open translation to cardiovascular signaling in vivo.
Hormonal stimulation of isolated hepatocytes evokes complex time-course changes in K and Cl conductances, likely driven by intracellular second-messenger concentrations.
Capiod et al. (1989) studied this question.
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