This basic science study demonstrates that the N-terminal segment containing the translation initiation site of the encephalomyocarditis virus capsid precursor is cleaved and not conserved in mature capsid proteins.
Translation of encephalomyocarditis virus RNA in rabbit reticulocyte lysates in the presence of N-formyl-[(35)S]methionine-tRNA(f) (Met) revealed that a small polypeptide is cleaved from the N-terminus of the capsid protein precursor, preA, by virus-coded protease activity. Therefore, this N-terminal segment comprising the translation initiation site is not conserved in any of the mature capsid proteins.
No takes yet. Share an insight, caveat, or question.
Campbell et al. (1983) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: