Why the study?
How do physiological parameters of ileo-pouch-anal function in patients after restorative proctocolectomy compare to normal controls?
Population
30 patients after restorative proctocolectomy and age- and sex-matched controls
Comparison
Restorative proctocolectomy and ileo-pouch-anal… vs Age- and sex-matched controls
Design
Case-control
Authors
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Lower pressures and compliance may compromise pouch function; leaves open their predictive value for outcomes after restorative proctocolectomy.
How do physiological parameters of ileo-pouch-anal function in patients after restorative proctocolectomy compare to normal controls?
Restorative proctocolectomy with ileo-pouch-anal anastomosis significantly alters anorectal physiology, reducing anal canal pressures and compliance compared to normal controls, with pelvic sepsis further increasing physiological abnormalities.
Keighley et al. (1988) studied this question.