May 28, 2002Circulation
Tea Consumption and Mortality After Acute Myocardial Infarction
Why the study?
Does tea consumption reduce long-term mortality in patients hospitalized with acute myocardial infarction?
Population
1900 patients hospitalized with a confirmed acute myocardial infarction between 1989 and 1994
Comparison
Self-reported usual weekly caffeinated tea… vs No tea consumption (nondrinkers)
Design
Cohort
Follow-up
median 3.8 years
Authors
Discussion
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Implication
Pre-MI tea intake was associated with lower post-MI mortality; hypothesis-generating and should not yet change practice.
Key Points
- To investigate the association between pre-infarction caffeinated tea consumption and subsequent long-term mortality among patients hospitalized with acute myocardial infarction.
- Prospective cohort study of 1900 patients hospitalized with confirmed acute myocardial infarction between 1989 and 1994 (Determinants of Myocardial Infarction Onset Study), followed for a median of 3.8 years.
- Self-reported caffeinated tea consumption in the prior year was categorized as nondrinkers (n=1019), moderate (<14 cups/week, n=615), or heavy (≥14 cups/week, n=266).
- Cox proportional hazards regression models estimated long-term total and cardiovascular mortality, adjusting for age, sex, clinical, and sociodemographic covariates.
- Age- and sex-adjusted mortality was significantly lower in moderate tea drinkers (HR 0.69; 95% CI, 0.53 to 0.89) and heavy tea drinkers (HR 0.61; 95% CI, 0.42 to 0.86) compared to nondrinkers.
- Multivariable adjustment for clinical and sociodemographic factors showed persistent reductions in mortality for moderate (HR 0.72; 95% CI, 0.55 to 0.94) and heavy tea drinkers (HR 0.56; 95% CI, 0.37 to 0.84).
- The inverse association between tea consumption and mortality was similar across both total and cardiovascular-specific mortality.
Structured PICO
Does tea consumption reduce long-term mortality in patients hospitalized with acute myocardial infarction?
P
Population
1900 patients hospitalized with a confirmed acute myocardial infarction between 1989 and 1994
I
Intervention
Self-reported usual weekly caffeinated tea consumption during the year before infarction (moderate: <14 cups/week; heavy: ≥14 cups/week)
C
Comparator
No tea consumption (nondrinkers)
O
Outcome
Long-term mortality (total and cardiovascular)hard clinical
Self-reported tea consumption in the year before acute myocardial infarction is associated with lower long-term mortality after infarction.
Cite This Study
Mukamal et al. (2002) studied this question.