Why the study?
Kinetics, moderators, and reference limits for exercise-induced cardiac troponin T elevations remained unclear in athletes.
Does acute endurance exercise increase high-sensitivity cardiac troponin T (hs-cTnT) concentrations in healthy athletes, and what are the kinetics and reference limits?
Population
1,421 athletes across 13 studies
Comparison
hs-cTnT concentrations before vs after a bout of exercise
Design
Systematic review and meta-analysis
Authors
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Transient post-exercise hs-cTnT rises warrant adjusted reference limits to avoid MI misdiagnosis in athletes; extends duration-dependent kinetics data.
Does acute endurance exercise increase high-sensitivity cardiac troponin T (hs-cTnT) concentrations in healthy athletes, and what are the kinetics and reference limits?
Acute endurance exercise induces a transient, physiological elevation in hs-cTnT that peaks around 3 hours and is moderated by exercise duration and modality, establishing new reference limits to prevent misdiagnosis of myocardial infarction in athletes.
Li et al. (2021) studied this question.
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