Why the study?
Does alloxan-induced diabetes impair aortic baroreceptor activity, renal sympathetic nerve activity, or vagal heart rate responses in rabbits?
Does alloxan-induced diabetes impair aortic baroreceptor activity, renal sympathetic nerve activity, or vagal heart rate responses in rabbits?
In a rabbit model of alloxan-induced diabetes, baroreceptor pressure-activity relations, arterial pressure-RSNA relations, and vagal heart rate responses were not significantly impaired compared to normoglycemic controls.
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Preserved baroreceptor sensitivity in this diabetic rabbit model does not support autonomic impairment; leaves open relevance to other species or diabetes models.
McDowell et al. (1994) studied this question.
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