Population
Acute (10-20 days) streptozotocin (STZ)-induced diabetic rats
Comparison
Streptozotocin (STZ)-induced diabetes vs Control animals
Design
Preclinical
Follow-up
10-20 days
Authors
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Baroreflex impairment in diabetic rats implicates efferent dysfunction; hypothesis-generating for mechanisms of autonomic neuropathy in human diabetes.
Short-term STZ-induced diabetes in rats impairs baroreflex sensitivity, likely due to dysfunction in the efferent limb of the baroreflex rather than baroreceptor function.
Silva et al. (2002) studied this question.
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