Population
Rabbits with chronic renal hypertension (4 months duration) and normotensive rabbits
Comparison
Afferent electrical stimulation of the left… vs Normotensive rabbits
Design
Preclinical
Follow-up
4 months
Authors
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Implicates central mechanisms in baroreflex impairment during chronic hypertension; leaves open translation to human disease.
Chronic renal hypertension of 4 months duration impairs baroreflex control of lumbar sympathetic nerve activity through an abnormality in the central nervous system mediation of the reflex.
Guo et al. (1984) studied this question.
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