Why the study?
Does renal hypertension alter the central arterial baroreceptor reflex control of renal nerve activity in rabbits?
Population
25 rabbits (14 normotensive and 11 with renal hypertension)
Comparison
Phenylephrine-induced increases in arterial… vs Normotensive rabbits
Design
Preclinical
Authors
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Central baroreflex impairment of renal nerve activity occurs in hypertensive rabbits; leaves open relevance to human hypertension mechanisms.
Does renal hypertension alter the central arterial baroreceptor reflex control of renal nerve activity in rabbits?
Renal hypertensive rabbits exhibit a central abnormality in the baroreflex control of renal nerve activity, characterized by impaired inhibition of renal nerve traffic during blood pressure increases.
Thames et al. (1984) studied this question.
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