November 1, 1984HypertensionOpen Access

Central effect of intravenous phenylephrine on baroreflex control of renal nerves.

View Full Paper

Ask AI

Bookmark

Population

Chloralose-anesthetized rabbits

Comparison

Phenylephrine infusion vs Baseline/control state

Design

Preclinical

Authors

TITakahiro ImaizumiNagoya University SBS D Brunk BGB. N. GuptaIndian Institute of Engineering Science and Technology, Shibpur

Discussion

Member takes

Implication

May guide mechanistic studies of vasopressor baroreflex effects; leaves open translation to human hypertension.

Structured PICO

Population

Chloralose-anesthetized rabbits (n=8 for main experiment, n=5 for isolated carotid baroreflex, n=9 for intracerebroventricular injection)

Intervention

Phenylephrine infusion (intravenous and intracerebroventricular)

Comparator

Baseline/control state

Outcome

Renal sympathetic nerve activity and baroreflex gainsurrogate

Intravenous phenylephrine alters arterial baroreflex control of renal nerves via a central mechanism in a rabbit model.

Cite This Study

Imaizumi et al. (1984) studied this question.

synapsesocial.com/papers/6a81642b046b5fb0cc649ced https://doi.org/10.1161/01.hyp.6.6.906

Topics

Hypertension management

View Full Paper

Ask AI

Bookmark

Central effect of intravenous phenylephrine on baroreflex control of renal nerves.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Central effect of intravenous phenylephrine on baroreflex control of renal nerves.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider