The Emerging Role of Nanotechnology in Cell and Organ Transplantation

In Brief Transplantation is often the only choice many patients have when suffering from end-stage organ failure. Although the quality of life improves after transplantation, challenges, such as organ shortages, necessary immunosuppression with associated complications, and chronic graft rejection, limit its wide clinical application. Nanotechnology has emerged in the past 2 decades as a field with the potential to satisfy clinical needs in the area of targeted and sustained drug delivery, noninvasive imaging, and tissue engineering. In this article, we provide an overview of popular nanotechnologies and a summary of the current and potential uses of nanotechnology in cell and organ transplantation. Tasciotti et al provide an exhaustive review how nanotechnology can be applied to address the grand challenges in cell and organ transplantation, including targeted and sustained drug delivery, noninvasive imaging and tissue engineering.