Clarithromycin, a macrolide antibiotic, can rarely cause acquired QT prolongation leading to potentially fatal torsades de pointes.
Acquired QT prolongation can be caused by cardiac and noncardiac medications. Macrolides are known to prolong QT interval. Rarely, it can be fatal. We report a case of torsades de pointes in a patient taking clarithromycin as a part of Helicobacter pylori eradication regimen.
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Chang et al. (2014) studied this question.
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