Why the study?
Do antibacterial drugs produce an effective reduction in the bacterial content of the intestine in patients about to undergo colonic surgery?
Do antibacterial drugs produce an effective reduction in the bacterial content of the intestine in patients about to undergo colonic surgery?
This editorial synopsis discusses the use of antibacterial drugs to reduce intestinal bacterial flora prior to colonic surgery.
EDITORIAL SYNOPSIS The authors, by qualitative and quantitative assessment of the bacterial flora of the large bowel pre-operatively and at operation, have determined the sensitivities of the various organisms found.They have then endeavoured to discover the best agents to produce an effective reduction in the bacterial content of the intestine in patients about to undergo colonic surgery.They state that in the majority of patients a combination of drugs such as framycetin, 2 g., and ampicillin, 1 g., or neomycin, 2 g., plus bacitracin 100,000 units, per day will be effective.
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Gunn et al. (1965) studied this question.
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