Why the study?
Does female sex increase mortality in children <18 years undergoing cardiac surgery?
Population
25,402 children <18 years undergoing cardiac surgery for congenital heart disease, based on California…
Comparison
Female sex vs Male sex
Design
Cohort
Follow-up
up to 30 days post discharge
Authors
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May inform sex-specific risk stratification in pediatric cardiac surgery; leaves open causality and need for prospective validation.
Does female sex increase mortality in children <18 years undergoing cardiac surgery?
Female sex is an independent risk factor associated with an 18% higher risk-adjusted in-hospital and 30-day postdischarge mortality in pediatric patients undergoing cardiac surgery.
Klitzner et al. (2006) studied this question.
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