September 1, 1993The Journal of PhysiologyOpen Access

Calcium currents elicited by voltage steps and steady voltages in myocytes isolated from the rat basilar artery.

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Population

Myocytes isolated from the rat basilar artery

Design

Preclinical

Authors

Discussion

May support resting tone in cerebral arteries; hypothesis-generating for window currents in human vasoregulation.

Population

Myocytes isolated from the rat basilar artery

Intervention

Whole-cell patch clamp recording in response to voltage steps or steady holding potentials, with varying concentrations of Ca2+, Ba2+, Co2+, and Mg2+

Outcome

Ca2+ channel currents (peak and steady-state)surrogate

Ca2+ channels in rat basilar arterial myocytes may provide a steady-state Ca2+ influx that contributes to resting contractile tone.

Langton et al. (1993) studied this question.

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