October 1, 1992The Journal of PhysiologyOpen Access

Voltage‐dependent sodium and calcium currents in cultured parasympathetic neurones from rat intracardiac ganglia.

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Population

Cultured parasympathetic neurones dissociated from neonatal rat intracardiac ganglia

Design

Preclinical

Authors

ZXZijian XuQingdao University DADavid J. AdamsUniversity of Wollongong

Discussion

Member takes

Implication

Does not inform clinical practice; extends ion current characterization in rat parasympathetic neurons for future autonomic studies.

Structured PICO

Population

Cultured parasympathetic neurones dissociated from neonatal rat intracardiac ganglia

Intervention

Voltage-clamp electrophysiology with ion substitution and pharmacological blockade (e.g., tetrodotoxin, Cd2+)

Outcome

Characteristics of depolarization-activated Na+ and Ca2+ currents (peak amplitudes, I-V curves, activation/inactivation kinetics)surrogate

This preclinical study characterizes the voltage-dependent sodium and calcium currents underlying the action potential in neonatal rat intracardiac parasympathetic neurons.

Cite This Study

Xu et al. (1992) studied this question.

synapsesocial.com/papers/6a7d2606e6f633beba6e4c07 https://doi.org/10.1113/jphysiol.1992.sp019344

View Full Paper

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Voltage‐dependent sodium and calcium currents in cultured parasympathetic neurones from rat intracardiac ganglia.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Voltage‐dependent sodium and calcium currents in cultured parasympathetic neurones from rat intracardiac ganglia.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider