Why the study?
Does a moderate fat meal increase platelet and monocyte activation in healthy normolipemic men?
Population
13 healthy, normal weight, normolipemic males, aged 20 to 49 years
Comparison
Consumption of a 40% fat meal of whole foods vs Fasting state (baseline)
Design
Cohort
Follow-up
6 hours
Authors
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A moderate-fat meal may acutely activate platelets and monocytes; hypothesis-generating for early atherogenesis and requires prospective confirmation.
Does a moderate fat meal increase platelet and monocyte activation in healthy normolipemic men?
A moderate fat meal induces acute activation of platelets and monocytes in healthy men, suggesting a potential early mechanism in the initiation and development of atherosclerosis.
Hyson et al. (2002) studied this question.
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