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August 6, 2002CirculationOpen Access

Results and Long-Term Predictors of Adverse Clinical Events After Elective Percutaneous Interventions on Unprotected Left Main Coronary Artery

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Population

67 consecutive patients with de novo lesions in unprotected left main coronary arteries

Design

Cohort

Follow-up

31+/-23 months

Authors

TTTakuro TakagiNew Tokyo HospitalGSGoran StankovićInterventional CardiologyLFLéo FinciAmerican College of Cardiology

Discussion

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Implication

Supports PCI feasibility in unprotected left main disease despite low procedural risk; leaves open durability versus CABG pending randomized trials.

Structured PICO

P
Population
67 consecutive patients with de novo lesions in unprotected left main coronary arteries
I
Intervention
Elective percutaneous coronary intervention (39 with stents, 12 with rotational atherectomy plus stents, 13 with directional coronary atherectomy plus stents, and 3 with directional coronary atherectomy only)
O
Outcome
Cumulative adverse clinical events (death, cardiac death, myocardial infarction, and repeat revascularization) at 31+/-23 months follow-uphard clinical

Elective percutaneous coronary intervention for unprotected left main coronary artery disease is feasible with low procedural risk, but is associated with high long-term rates of angiographic restenosis and repeat revascularization.

Cite This Study

Takagi et al. (2002) studied this question.

synapsesocial.com/papers/6a83bb8cf4298de60b3c27bdhttps://doi.org/10.1161/01.cir.0000024983.34728.5d
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effect of an Aggressive Lipid-Lowering Strategy on Progression of Atherosclerosis in the Left Main Coronary Artery From Patients in the Post Coronary Artery Bypass Graft Trial2001 · 58 citations
  2. 2Intracoronary Stenting Without Anticoagulation Accomplished With Intravascular Ultrasound Guidance1995 · 1,427 citations
  3. 3Long-Term Clinical Outcomes After Unprotected Left Main Trunk Percutaneous Revascularization in 279 Patients2001 · 239 citations
  4. 4A prospective study of elective stenting in unprotected left main coronary disease1999 · 49 citations