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July 1, 2020TH OpenOpen Access

Clinical Utilization and Cost of Thrombophilia Testing in Patients with Venous Thromboembolism

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Why the study?

Testing for inherited and acquired thrombophilias adds to the cost of care in VTE patients, though results may not influence patient management.

Does thrombophilia testing in patients with VTE impact clinical management and what are the associated costs?

Population

266 eligible patients with VTE at Emory University Hospitals

Comparison

Patients undergoing thrombophilia testing vs those not tested

Design

Single-center retrospective study

Authors

MGManila GaddhECEn ChengMEMaha AT Elsebaie

Discussion

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Member takes

Overview

Routine thrombophilia testing rarely alters VTE management at high cost; leaves open value of targeted strategies.

Structured PICO

Does thrombophilia testing in patients with VTE impact clinical management and what are the associated costs?

P
Population
266 patients with venous thromboembolism (VTE) at Emory University Hospitals
I
Intervention
Thrombophilia testing
C
Comparator
No thrombophilia testing
O
Outcome
Pattern of thrombophilia testing, impact on clinical decision-making, and direct costs

Thrombophilia testing in VTE patients is frequently performed but rarely impacts clinical management, resulting in high healthcare costs.

Cite This Study

Gaddh et al. (2020) studied this question.

synapsesocial.com/papers/6a83bbb882dd948707b05945https://doi.org/10.1055/s-0040-1714334
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Thrombophilia testing in people with venous thromboembolism: systematic review and cost-effectiveness analysis2009 · 34 citations
  2. 2Guidance for the evaluation and treatment of hereditary and acquired thrombophilia2016 · 345 citations
  3. 3An Evaluation of Thrombophilia Screening in an Urban Tertiary Care Medical Center: A "Real World" Experience2006 · 27 citations
  4. 4Risk Factors for Venous Thromboembolism2003 · 1,665 citations
  5. 5Thrombophilia testing in children: A 7 year experience2013 · 18 citations