Population
8,110 men aged 40-59 years at entry from northern European cohorts and southern European cohorts
Design
Cohort
Follow-up
10 years
Authors
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Applying northern European CHD risk models southward may overestimate absolute risk; supports region-specific calibration but requires prospective validation.
Coronary risk charts should incorporate coefficients to correct for different background incidence rates across different European cultures to avoid over- or underestimating absolute risk.
Alessandro Menotti (2000) studied this question.
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