Why the study?
Is growth hormone replacement therapy safe in adults with severe growth hormone deficiency?
Is growth hormone replacement therapy safe in adults with severe growth hormone deficiency?
This review discusses the safety of long-term growth hormone replacement therapy in adults with severe growth hormone deficiency, focusing on metabolic and neoplastic risks.
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Long-term GH replacement safety data remain inconclusive; leaves open metabolic and neoplastic risk assessment in severe GHD.
Gibney et al. (2004) studied this question.
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