Key result
Growth hormone replacement therapy in adults with growth hormone deficiency improves body composition, muscle mass, and quality of life, though long-term risks require ongoing evaluation.
This review summarizes the established benefits, potential long-term risks, and molecular aspects of growth hormone replacement therapy in adults with growth hormone deficiency.
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GHRT may benefit body composition in GHD adults; leaves open long-term safety assessment in prospective trials.
Díez et al. (2018) conducted a review in Growth hormone deficiency (GHD) in adults. Growth hormone replacement therapy was evaluated. Growth hormone replacement therapy in adults with growth hormone deficiency improves body composition, muscle mass, and quality of life, though long-term risks require ongoing evaluation.
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